How Much Does GLP-1 Cost? Complete 2025 Guide

Quick Answer

GLP-1 medications cost $1,000–$1,400 per month at US list price without insurance. Wegovy lists at approximately $1,349/month; Zepbound at approximately $1,059/month. With manufacturer savings cards, commercially insured patients often pay $25–$100/month. Without insurance, out-of-pocket costs are the most significant barrier to access.

List Prices for GLP-1 Medications (2025)

Medication	Brand	Indication	Monthly List Price
Semaglutide 2.4 mg	Wegovy	Obesity	~$1,349
Semaglutide 1–2 mg	Ozempic	Diabetes	~$935
Tirzepatide 15 mg	Zepbound	Obesity	~$1,059
Tirzepatide 15 mg	Mounjaro	Diabetes	~$1,023
Liraglutide 3 mg	Saxenda	Obesity	~$1,350
Semaglutide oral	Rybelsus	Diabetes	~$931

These are US list prices (MSRP) before insurance. Actual out-of-pocket costs vary dramatically based on insurance coverage, manufacturer programs, and pharmacy choice.

With Insurance: What Do People Actually Pay?

Insurance coverage for GLP-1 medications has expanded significantly but remains inconsistent:

Commercial insurance (employer plans):

Coverage rates for obesity medications have increased but still vary by employer
Plans that cover Wegovy/Zepbound typically require prior authorization and documentation of obesity with BMI criteria
After savings card: as low as $25/month with the Novo Nordisk or Eli Lilly programs

Medicare Part D:

Part D now covers Wegovy for cardiovascular risk reduction (since 2024, following the SELECT trial)
Coverage for obesity treatment per se is still more limited under Medicare
Typical Medicare patient cost: $100–300/month depending on plan and coverage tier

Medicaid:

Coverage varies enormously by state
Some state Medicaid programs fully cover GLP-1 medications; others exclude obesity indications

No insurance / uninsured:

Full list price applies: $1,000–1,400/month
Manufacturer assistance programs can help qualifying low-income patients

Manufacturer Savings Programs

Both major manufacturers offer savings programs:

Novo Nordisk (Wegovy/Ozempic):

Savings card: eligible commercially insured patients can pay as little as $25/month
NovoCare patient assistance: free or discounted medication for uninsured patients below income thresholds

Eli Lilly (Zepbound/Mounjaro):

Lilly Savings Card: up to $573/month off; eligible patients pay as little as $25/month
Zepbound Savings Vials: Eli Lilly launched single-dose vials in 2024 at $399–549/month for self-pay patients

Telehealth Platform Pricing

Online weight loss platforms often offer bundled pricing that includes:

Medical evaluation and ongoing provider access
Prescription management
Sometimes discounted medication supply

Typical bundled pricing ranges from $200–600/month depending on the platform and medication included. Compounded semaglutide platforms are generally at the lower end; branded medication platforms are higher.

Reducing GLP-1 Costs: Practical Options

Use manufacturer savings cards first. Both Novo Nordisk and Eli Lilly programs are accessible online. If you have commercial insurance, apply immediately — savings can be $1,000+/month.

Compare pharmacies. GLP-1 prices vary by pharmacy. Mark Cuban's Cost Plus Drugs, pharmacy chains, and specialty pharmacies can differ significantly. GoodRx coupons sometimes apply.

Discuss Mounjaro vs. Zepbound with your provider. Mounjaro (diabetes-approved tirzepatide) sometimes has different insurance coverage than Zepbound, even with the same active ingredient.

Ask about income-based assistance. Both manufacturers have patient assistance programs for uninsured or underinsured patients below specific income thresholds.

Get GLP-1 at Lower Cost Through a Telehealth Provider

Bottom Line

GLP-1 list prices are high — $1,000–1,400/month — but most commercially insured patients who use manufacturer savings programs pay $25–100/month. The biggest cost barrier exists for uninsured and Medicare patients. Manufacturer assistance programs, telehealth bundles, and self-pay vial options are expanding access.